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At least I have heard it several times I've read that pretty much generic is plus/minus 7mcg while Synthroid would likely be plus/minus 5mcg (random numbers). You get the same concentration of medication and such. Synthroid is so much more effective. Except with Levothyroxine/Synthroid. I believe that the levothyroxine I am taking is a generic form of Synthroid. For example, 100 mcg generic levothyroxine could contain up to 125 mcg per pill from one manufacturer or as low as 75 mcg from another. There can be subtle differences from manufacturer to manufacturer in the actual dosage. 4 mIU/L) for at least 3 months before either continuing to take the same product or switching among generic levothyroxine products (index date).. I was feeling so crappy before starting, I didn't want to take any chances Just today, I picked up what I thought was my Synthroid refill to find out it was generic, very upset, 90 days worth, can't return it, most likely …. Generic Levothyroxine Ericamegan My endo recommended that I take Synthroid instead of the generic. When you stick with one name brand, you can be assured that every time you fill that prescription at the pharmacy that every pill of, say, 100 mg of Synthroid is going to be the same Synthroid VS Levothyroxine. Levothyroxine is one of the most prescribed medications in the ent. Generic meds (even antibiotics, etc) in general can be off up to 20-25 % in active ingredient. Hi, I was just diagnosed as hypo on Monday and started meds. However, if you're still having symptoms, it may be worth trying Synthroid to see if it helps you. This is an extreme, worst case scenario. Just today, I picked up what I thought was my Synthroid refill to find out it was generic, very buy persantine online with free samples upset, 90 days worth, can't return it, most likely …. I have had two friends tell me to call the pharmacy and switch to real Synthroid. She said this is one of the only drugs she really recommends not to take the generic. Many will not prescribe anything else. These results suggest that generic levothyroxine as initial therapy for mild thyroid dysfunction is as effective as brand-name levothyroxine. 2 out of 10 from a total of 805 ratings on Drugs. The generic is not even close for effectiveness. She said she has seen some patients that don't absorb the generic as well. I know of no one who has had positive response using generic form and quite the opposite for those on Synthroid. If your TSH/T3/T4 are doing fine on levothyroxine, that makes it seem like the generic is doing fine for you. Publication types Comparative Study. I really didn't notice any side effects from the generic but since switching to the name brand I have begun having hot flashes and night sweats (I'm WAY past menopause) and I feel anxious, moody, my foot is constantly moving when I'm sitting and recently I noticed I'm clenching my teeth.. But since the dose of what the thyroid needs is so. Synthroid vs Levothyroxine: which is best? I was recently switched to the name brand of Synthroid after taking the generic for 20 + years. Synthroid releases it's TSH over a period of 16-18 hours so when it's reaching the period where it's not in your bloodstream any more, it's time for your next morning dose. Most generic medications are more or less the same. I was prescribed generic levo but I know my mom (longtime hypo) made me go get synthroid prescribed the next week lol GE. I was prescribed generic levo but I know my mom (longtime hypo) made me go get synthroid prescribed the next week lol Synthroid vs. Synthroid is the brand name of the drug and most doctors consider it the "gold standard" in treating hypothyroidism. To the best of my knowledge, the reason you must have your blood tested if the brand of levothyroxine you are taking changes is because there is a 5% plus or minus difference in the amount of medication absorbed between manufacturers Synthroid vs. Synthroid and Levothyroxine are both considered T4 only thyroid medications which means that they contain the bio-identical thyroid hormone Thyroxine. These two thyroid medications are NOT the same. Liothyronine, on the other hand, contains the most potent thyroid hormone which is known as T3 or triiodothyronine. Adults aged 18 years or older were included if they filled a generic levothyroxine prescription between January 1, 2008, and June 30, 2019, and had a stable drug dose, the same drug manufacturer, and a normal TSH level (0. I have found, and my doctor reached the same conclusion, that levothyroxine releases all of the TSH over a period of 6-8 hours, then you go 16-18 hours with no TSH. T3 is about 3-4 times more powerful than T4 (depending on which study you look at) Lower-cost generic is available Ratings & Reviews Levothyroxine has an average rating of 5. Levothyroxine is also available under other brand names, including Tirosint® and Levoxyl® Brand vs. On the other hand, it's more expensive than the generic levothyroxine, so most insurance companies want their clients to take the generic. The generic caused an increase in their symptoms, weight gain and not much affect on their numbers Conclusions and relevance: Initiation of generic vs brand-name levothyroxine formulations was associated with similar rates of normal and stable thyrotropin levels. I've also read that synthroid comes from one company while generics can come from a multitude of companies. The down side of Synthroid is that it is more expensive, usually While the dosage in each brand or generic is the same, the fillers and the way they are dissolved in your body can be very different. Generic: What the Research Says According to a presentation at the annual meeting of the American Association of Clinical Endocrinologists in 2017, Synthroid was associated with significantly better thyroid-stimulating hormone (TSH) lab results than generic levothyroxine.